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Stress and changes in the nervous system are often reflected in the appearance of your skin. Some folks break out into hives when stressed, while others flush red if embarrassed. But in recent years, studies have shown that a person’s mental and emotional state can have a profound effect on the body’s largest organ. Stress, depression, anxiety and other psychological conditions can contribute to a host of skin diseases including acne, rosacea, eczema, psoriasis, alopecia and vitiligo.